Your biology,
resolved into a graded plan.
Crebral Health reads each patient's bloodwork and biological age, then assembles an editable, evidence-graded program — and runs the whole clinic around it.
Frontier-inclusive · honestly graded · practitioner owns every plan.
One patient's bloodwork in. A tiered, cited plan out.
The strand becomes a readout. Every panel is scored against optimal — not just lab-normal — ranges, then graded, sourced, and assembled into a plan you edit and approve.
The engine pulls graded claims from a 473-claim corpus — every line carries its grade, source, and frontier flag.
Each biomarker is read against optimal ranges, with inline trends — click any value to open the full longitudinal history.
A Foundation → Targeted → Frontier plan is drafted and cited. You edit and approve. The final call stays yours.
Built for the frontier of longevity care.
Crebral Health is made for practices that already work past the lab-normal floor — compounded peptides, hormone optimization, metabolic and incretin therapy, advanced diagnostics. It gives that work an evidence spine: every lever graded, sourced, and labeled, so you can be ambitious and defensible at once.
Longevity & anti-aging clinics
Translate biological-age testing and deep panels into a structured, tiered program — instead of a stack of disconnected recommendations.
Functional & precision medicine
Optimal-range scoring, longitudinal trends, and retest scheduling built in — the rigor your model of care already demands.
Performance & healthspan
Frontier interventions are surfaced and clearly labeled — never hidden, never overstated — so you can push the edge responsibly.
One engine. Three ways in.
Same patient, same bloodwork — choose how the program is anchored. The combined synthesis is the flagship: the single best graded plan, fused from every expert, the current frontier, and the peer-reviewed literature.
Combined synthesis
Every expert, the current frontier, and the peer-reviewed evidence blended into the single best graded plan for this patient's biomarkers.
Expert lens
Anchor the plan to a named expert's protocol, then adapt it to the labs in front of you — nine lenses to choose from.
Practitioner-seeded
Set your constraints — peptide-forward, no hormones, whatever fits — and the engine fills in the rest, graded and cited.
Watch the number that actually moves.
DNA-methylation and biological-age clocks sit alongside the bloodwork, mapped to the interventions that move them — so a program is judged on whether the patient is getting biologically younger, not just on labs landing in range.
Established levers first. Frontier, labeled — never hidden.
Same engine, one honest structure: a Foundation that holds, Targeted moves driven by the labs, and Frontier options surfaced — never buried, never dressed up as settled.
Broadly-indicated
Established levers with the deepest evidence base — the floor every program stands on.
Biomarker-driven
Evidence-backed interventions chosen for the specific labs in front of you, with grades attached.
Experimental
Promising but contested — surfaced and clearly labeled, with counter-evidence on the record.
A defensible knowledge base, not a chatbot guess.
The moat is the corpus. Every claim is graded A–X, flagged peer-reviewed or frontier, mapped to biomarkers, and sourced to primary literature. The engine retrieves from it — so you can show a patient exactly why, and stand behind every line.
Expert lenses
Nine longevity experts' protocols distilled into structured, comparable, citable claims.
Counterpoints on the record
Where the science is contested, the opposing evidence is captured with its verdict — not quietly dropped.
Aging clocks
DNA-methylation and biological-age clocks mapped to the interventions that actually move them.
A living corpus
473 graded claims today, each tied to peer-reviewed or frontier sources — reviewed and grown over time.
Ask Sasha. Grounded, cited, page-aware.
Sasha — a Scientific Assistant for Safe Health Answers — replies from your validated corpus, not an open-web guess. It knows which patient you're looking at, pulls graded claims with their citations, and runs anything it surfaces through the safety engine before it says a word.
Answers from the corpus
Every reply is drawn from graded, cited claims — grade and source shown. When the evidence isn't there, it says so instead of inventing it.
Knows this patient
Page-aware on every chart — it grounds answers in the patient's own labs, risk scores, medications, and conditions.
Safety-checked first
Any intervention it raises runs through the deterministic safety oracle, with contraindications flagged inline.
A light-EHR built around the program.
Not a generic EHR with a wellness skin. Every surface exists to draft, run, and follow up on evidence-graded plans — so the program isn't a document that gets filed and forgotten.
Longitudinal labs
Every panel scored against optimal — not just lab-normal — ranges. Drop a lab PDF or a FHIR export and it files itself into the trend. Click any value to open the full history.
Scheduling
Drag-to-reschedule, 15-minute precision, status tracking.
Proactive worklists
Who's coming in next and who's overdue for a retest — so follow-ups don't slip.
Patient charts
A complete, editable record — and every program a patient has run on their bloodwork.
Intake
Structured intake flows straight into the chart — the engine starts from real context, not a blank page.
Lab orders
Order the panels a program calls for and close the loop when results return.
The program follows the patient home.
A white-label portal and a native iOS app keep the plan, the labs, and the conversation in the patient's hands — and stream their real-world data back into the chart.
Patient portal
Their programs, results, and documents in one branded place — with secure two-way messaging to the practice.
Crebral for iPhone
A native app that streams Apple Health — sleep, HRV, activity, resting heart rate — straight from the patient's own device into the longitudinal chart.
Wearables on the chart
Recent trends sit beside the bloodwork and clocks, so a program is judged on how the patient actually lives — not one blood draw.
What's live, and what's coming.
32 capabilities live today, 1 in progress, 18 on the roadmap. Our next chapter: expanding the Longevity Risk Panel — validated, organ-system risk scores, auto-fed from each patient's vitals and labs and threaded into the program engine.
Safety & interaction governance
A deterministic safety net — every recommendation checked against meds, conditions, and labs.
- Interaction & contraindication oracle
- In-program safety check
- Coverage harness
- Specialist review console
- Per-specialty review queues
Longevity Risk Panel
Validated, organ-system risk scores — each auto-fed from vitals + labs and threaded into the engine.
- Cardiovascular risk (PREVENT ASCVD)
- Fracture risk (Garvan)
- Liver fibrosis (FIB-4)
- Kidney-failure risk (KFRE)
- Metabolic / diabetes risk
- Cognitive risk (CAIDE)
- Cancer risk models
Each risk score is validated against its reference tool, exactly as the AHA PREVENT/ASCVD calculator was.
One engine, priced to your practice.
A platform base, a seat for every practitioner, and graded programs that scale with your patient load. Every plan includes the evidence engine, scheduling, and longitudinal labs — annual billing saves 17%.
- Evidence-graded program generation
- Scheduling & patient tracking
- Longitudinal labs (manual upload)
- 1 biological-age clock
- Healthie & Practice Better integrations
- HIPAA BAA included
- Everything in Starter, plus:
- White-label patient portal
- Full lab integrations (Rupa / Fullscript / Quest)
- 3 biological-age clocks
- + Elation, Cerbo & Athena EHRs
- Dedicated onboarding
- Everything in Clinic, plus:
- SSO (SAML / OIDC) & audit logs
- Unlimited biological-age clocks
- HL7 FHIR & custom integrations
- Dedicated CSM & SLA
- Guided implementation
Graded programs are engine-generated, practitioner-reviewed outputs — every plan stays editable and cited. Prices in USD; taxes may apply.
Frontier-inclusive. Honestly graded. Practitioner-owned.
The engine is built to make you more confident, not to replace your judgment. It never hides what's experimental, never invents evidence, and never issues the final word — you do.
Honest grading
Every line carries its evidence grade and a peer-reviewed or frontier flag. Nothing experimental is dressed up as settled.
Human-in-the-loop
The engine drafts; you edit, augment, and approve. Every field is yours to change before anything is final.
Educational, not medical advice
Crebral Health is a research and education platform. The practitioner reviews and owns every plan.
Run your next patient through the engine.
Upload bloodwork, choose an anchor, and get an editable, graded, cited program in minutes — with the whole clinic built around it.